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Transfeminine Science is a resource for original informational content on the subject of transfeminine hormone therapy. This form of hormone therapy is also known variously as feminizing hormone therapy (FHT), gender-affirming hormone therapy (GAHT) for transfeminine people, and, more in the past, male-to-female (MtF) hormone replacement therapy (HRT). It involves the use of female sex hormones including estrogens and progestogens, as well as androgen-opposing medications known as antiandrogens, to produce feminization, demasculinization, alleviation of gender dysphoria, and other changes in transgender women and non-binary transfeminine individuals.

Transfeminine Science was created by Aly and contains articles by different writers on transfeminine hormone therapy. Our authors and other information are listed on our About page. The content on this site is written by transgender people, for transgender people, as well as for medical providers and academics in transgender health. A categorized listing of articles on Transfeminine Science can be found on the Articles page, while a listing of articles by date can be found on the Latest page. The Misc page contains other content like useful tools, notable publications, and links. The articles on this site are wiki-esque living documents, and hence may be updated, expanded, and improved over time.