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For an overview and description of Transfeminine Science, please visit our Home page.


Transfeminine Science originated out of the informational content on transfeminine hormone therapy that was created by informed transfeminine people in the r/MtFHRT community (now r/TransfemScience) on the social media website Reddit. For some more details, please visit our Announcement article.


The writers for Transfeminine Science at this time are Aly, Lain, and Sam.

Aly W.

Aly (“she/her”) is a transgender woman from Southern California. She has a passionate interest in transfeminine hormone therapy. Aly began her transition in 2012 and has been studying the transgender medical literature since. She has a bachelor’s degree in psychology summa cum laude from the University of California, Irvine. Aly also completed some of the pre-medicine curriculum and worked for about a year as an appointed volunteer in cognitive science research labs at UC Irvine.

Aly has been a volunteer editor on the English Wikipedia for many years. She was one of the top six medical editors for the online encyclopedia each year from 2015 to 2018. Aly has contributed a large amount of content to Wikipedia in the area of sex hormone pharmacology over the years. See her edit stats, top edited pages, articles created, and image uploads (alt) for a catalogue of her work.

Aly has founded and moderated a number of communities on Reddit that relate to transgender hormone therapy. Her username on Reddit is u/Alyw234237 and she created r/TransBreastTimelines and r/AskMtFHRT and formerly moderated r/TransDIY. Aly continues to serve as a moderator of r/TransfemScience as well as r/MtFHRT (previously the Reddit home of Transfeminine Science).

Aly can be reached via her social media accounts or by email at

➜ Articles by Aly W.

Lain M.

Lain (“they/them”) is non-binary and transfeminine. They completed a bachelor’s degree in applied mathematics and studied bioinformatics and computational biology at the Rochester Institute of Technology in New York. After withdrawing from their Ph.D. program, Lain migrated to the much warmer climes of the San Francisco Bay Area to work in tech.

As a person entrenched in nightlife community, specifically raving, Lain reformed and ran a nightlife harm reduction non-profit chapter for over 3 years, Bay Area DanceSafe ( At DanceSafe they produced harm reductive literature on pertinent drugs and organized harm reduction booths at various festivals and raves. Through this direct outreach to the nightlife community, Lain led volunteers providing peer education on drugs, consent, sex education, and other pertinent topics as well as substance adulterant testing and harm reduction interventions. As a chapter head, they advocated for the normalization of harm reduction and the reform of drug policy working with peer organizations such as the Drug Policy Alliance (DPA), the Students for Sensible Drug Policy (SSDP), the Multidisciplinary Association for Psychedelic Studies (MAPS), and also by speaking at several events in the Bay Area.

As Lain began to medically transition, they began to passionately research endocrinology and transgender medicine. They go by u/Klafka612 on Reddit and moderate several subreddits related to transgender hormone therapy including r/TransfemScience, r/AskMtFHRT, and r/TransBreastTimelines.

Lain can be reached via their social media accounts or by email at

➜ Articles by Lain M.

Sam S.

Sam (“she/her”) is a transgender woman from London, United Kingdom. She has no formal medical or research qualifications, but has an intense interest in evidence-based medicine and adherence to the scientific method and has contributed several articles on the subject of transfeminine hormone therapy to Transfeminine Science. Her major research interests include the relatively uncommon to rare adverse effects of hormone therapy in transfeminine people, such as thromboembolism and other cardiovascular diseases. Specifically, she is interested in how the safety of different gender-affirming hormone therapy medications and dosages might compare. Sam has been reading and keeping up to date with the formal medical literature since she began to hormonally transition in 2018.

Sam is active on Reddit as u/Samanthas2000, currently moderating a number of subreddits including r/TransfemScience, r/TransDIY, r/TransBreastTimelines and r/AskMtFHRT. She is also active on the instant messaging platform Discord. Sam can be reached by email at or on Discord with the user tag Samanthas2000#3719.

➜ Articles by Sam S.


If you would like to contact Transfeminine Science or one of our authors, we can be reached via social media (Reddit, Facebook, Messenger, Twitter). Alternatively, the authors of Transfeminine Science can be reached via their Transfeminine Science email addresses (listed above) and individual social media accounts (e.g., on Reddit or Discord). We welcome feedback on our content and other inquiries.

If you like the content on Transfeminine Science and would like to support or give back to an author for their work, we accept donations. You can donate to Aly W. using Buy Me a Coffee or Bitcoin. If you would like to donate to another one of Transfeminine Science’s writers, please contact them and this can be arranged. We greatly appreciate any support that we receive. 💜


Transfeminine Science is open to new content and contributors! If you are interested in potentially writing an article for the site or contributing regularly, please contact us. Please note that content will need to conform to our format and standards and will be informally peer-reviewed prior to acceptance.