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Transfeminine Science is a resource for original informational content on the subject of transfeminine hormone therapy. This form of hormone therapy is also known variously as feminizing hormone therapy (FHT), gender-affirming hormone therapy (GAHT) for transfeminine people, and—more in the past—male-to-female (MtF) hormone replacement therapy (HRT). It involves the use of female sex hormones including estrogens and progestogens—as well as androgen-opposing medications known as antiandrogens—to produce feminization, demasculinization, and alleviation of gender dysphoria in transgender women and non-binary transfeminine individuals.

Transfeminine Science contains articles by different writers on the subject of transfeminine hormone therapy. Our authors and their information are listed in the Authors section of the About page. Transfeminine Science is written by transgender people, for transgender people—and for their medical providers. A categorized listing of articles on the site can be found on the Articles page. In addition, a listing of articles by date with the most recent articles first can be found on the Latest page. The Misc page contains miscellaneous content like useful tools, notable publications, and links. The articles on this site are wiki-esque living documents and hence may be updated, expanded, and improved over time.